next up previous
Next: Multiple alignment with considerably Up: DeepForest: a Molecular Evolutionary Previous: Generation of huge bibliography

Semi-automatic multiple alignment

Multiple alignment is a critical step to reconstruct molecular phylogenetic trees. However, it is not easy to perform multiple alignments in considerably diverged genes. So far, putative conserved regions were often extracted by hand, and were multiple aligned. However, such an intuitive method might cause loss of critical information in sequences. To obtain good multiple alignments from considerably diverged sequence data, such as myosin heavy chain, it is needed to categorize the data according to their expected homologies.



 

Satoshi OOta
1999-03-06